Bin Gu, Ph.D.

Dr.Gu is an Assistant Professor in the Department of Obstetrics, Gynecology and Reproductive Sciences. He joined MSU from the Hospital for Sick Children, Toronto, Canada. Bin has developed the 2-cell(2C)-Homologous Recombination(HR)-CRISPR technology (Gu B. et al. Nature Biotechnology 2018), enabling efficient generation of large fragment knock-in reporter mice. The technology has been broadly adopted by the transgenic technology community to generate knock-in mouse models.  Bin has won a Young Investigator Award from the International Society for Transgenic Technology in 2019, recognizing the 2C-HR-CRISPR technology.  Building on this expertise, Bin is developing more genome editing technology for generating complex mutations such as segmental duplication and chromosome translocation in mouse models and use these models to study human diseases.  As a faculty adviser to the MSU-TGEF, he will provide advice for the adoption and development of cutting-edge genome editing technologies in animal model production and consult on projects aiming to generate challenging modifications.