Transgenic and Genome Editing Facility

Bin Gu, Ph.D.

Dr.Gu is an Assistant Professor in the Department of Obstetrics, Gynecology and Reproductive Sciences. He joined MSU from the Hospital for Sick Children, Toronto, Canada. Bin has developed the 2-cell(2C)-Homologous Recombination(HR)-CRISPR technology (Gu B. et al. Nature Biotechnology 2018), enabling efficient generation of large fragment knock-in reporter mice. The technology has been broadly adopted by the transgenic technology community to generate knock-in…

Bana Abolibdeh

Bana completed her undergraduate work in Biochemistry and Molecular Biology and her Master’s degree in Laboratory Research in Pharmacology and Toxicology at Michigan State University where her worked focused on investigating factors affecting vascular cognitive impairment development in overweight rodent models. Bana is the lab manager of the Transgenic and Genome Editing Facility (TGEF) and the Stem Cell Core (SCC). Her current work at the TGEF involves performing…

Elena Demireva, PhD

Portrait photo of Elema Demireva

Dr. Demireva obtained her HBSs in Molecular Biology and Molecular Genetics from the University of Toronto.  She joined Columbia University’s Center for Neurobiology and Behavior for her graduate work in neuroscience, where she studied the molecular determinants of motor circuit assembly in the developing spinal cord. Conducting these studies Elena learned the intricacies of transgenic mouse construction, molecular biology, neuroanatomy, circuit analysis,…

Huirong Xie, PhD

Portrait photo of Huirong Xi

Dr. Xie completed her undergraduate work in Biology and her PhD in Reproductive Endocrinology at China Agricultural University, and conducted her postdoctoral work at Vanderbilt University Medical Center and Cincinnati Children’s Hospital Medical Center, in Reproductive Sciences. Dr. Xie was a key member of the transgenic facility at CCHMC that has successfully generated over a 100 animal lines by CRISPR/Cas editing. Dr….